what is a pharmacogenetics panel?

The pharmacogenetic (PGx) panel assesses for variants in 26 specific genes known to play a role in medication metabolism. PGx testing is just one aspect of personalized medicine, and results may aid in medication choice and dosage. This can help improve efficacy and reduce adverse effects more quickly than the typical “trial-and-error” approach to prescribing medications. Regardless, response to medications is complex and may also be influenced by factors which are not looked at by PGx. No one should ever stop or change their medication choice or dosage without first speaking with their healthcare provider.

This test might be appropriate when:
  • Medication is being prescribed and more information could be useful
  • Trials of medications have failed
  • PGx tests can usually inform on some medications in different classes:
    • Stimulants (certain ADHD medications)
    • Anti-seizure
    • Antipsychotics
    • Anti-anxiety/depression
    • NSAIDs
    • Statins (cholesterol lowering)
    • Blood pressure regulation
    • Antidiabetics
    • Opioids
    • Proton pump inhibitors (for reflux)
    • Antihistamines

Accepted Specimens
  • Saliva via a buccal swab
  • Whole blood
  • Extracted DNA

Clinical Support for Pharmacogenetics Panel

Bionano Laboratories offers unlimited clinical support to patients and providers through access to our genetic counselors who can discuss testing capabilities, strategy, informed consent, and results.

Providers can call our genetic counselors at


Common variants in the following genes are assessed:

CYP2D6, CYP3A5, CYP2C19, SLCO1B1, CYP2C9, COMT, VKORC1, CYP2B6, CYP1A2, OPRM1, CYP3A4, ABCG2, F2, F5, HLA-A *31:01, HLA-B*15:02, ABCB1, ADRA2A, APOE (526C>T), CES1A1, DRD2, HTR2A, MTHFR (C677T), SLC6A4, UGT1A4, UGT2B15

Click Here To View The Full List Of Reported Medications

This test is comprised of the Veridose Core and Veridose CYP2D6 CNV panels developed by Agena. The genomic regions listed in this report were tested using the Agena MassARRAY® System. There is a possibility that the tested individual is a carrier for additional undetected variants that may affect results. Allergic reactions cannot be detected by this genetic test. The test does not detect all known variants in the genes tested.

How do I know if the test will be relevant for the medications I’m interested in?

All medications known to have a firm association with a specific genotype can be found using our GeneSearch tool, under the “Pharmacogenetics Medication Search Tool” tab located here.

What do I do with the results?

Ordering providers are encouraged to submit a patient’s current medication list at the time of the test request. Once results are issued, you will find that our reports utilize a red-green-yellow categorization system to make results visually simple. Additionally, any personalized information available regarding the submitted medication list is described. This may include drug-gene interaction information or published dosing guidelines. Lastly, both providers and patients have access to a certified team of genetic counselors to review results at their convenience.
To schedule an appointment, please call 801.931.6191 or schedule online.

Do I need a separate swab for PGx if I’m already ordering other tests?

No. If other tests are being ordered at the same time, such as FirstStepDx PLUS (chromosomal microarray) or Fragile X syndrome testing, PGx can be performed on the same cheek swab sample.